Refereed Research Papers
2024
Stykel MG; Siripala SV; Soubeyrand E; Camargo S; Lu P; Coackley CL; Panchal R; So RWL; Stuart E; Joseph J; Akrioti EK; Haji-Ghassemi O; Taoufik E; Akhtar T; Watts JC; Ryan SD
G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s Disease pathogenesis
Neuron, NEURON-D-23-01423 [In Revision]
Joseph TT; Bu W; Haji-Ghassemi O; Chen S; Woll K; Allen PD; Brannigan G; van Petegem F; Eckenhoff RG
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)
Br J Anaesth.133(5): 1093-1100.
2023
Cholak S; Saville JW; Zhu X; Berezuk AM; Tuttle KS; Haji-Ghassemi O; Alvarado F; Van Petegem F; Subramaniam S
Allosteric Modulation of Ryanodine Receptor RyR1 by Nucleotide Derivatives
Structure. 31(7): 790-800.e4.
2022
Qin, J; Zhang, J; Lin, L; Haji-Ghassemi, O; Lin, Z; Woycechowsky, KJ; Van Petegem, F; Zhang, Y; Yuchi, Z
Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy
eLife. 11: e75346.
Rayani, K; Hantz, E; Haji-Ghassemi, O; Yueh, AL; Spuches, A; Van Petegem, F; Solaro, JR; Lindert, S; Tibbits GF
The effect of magnesium on calcium binding to cardiac troponin C related hypertrophic cardiomyopathy mutants
FEBS J. 289(23): 7446-7465.
2021
2020
Stringer, RN; Jurkovicova-Tarabova, B; Huang, S; Haji-Ghassemi, O; Idoux, R; Liashenko, A; Souza, IA; Rzhepetskyy, Y; Lacinova, L; Van Petegem, F; Zamponi, GW; Pamphlett, R; Weiss, N
A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2 T-type channel activity
Mol Brain. 13(1): 1-11.
Ma, R*; Haji-Ghassemi, O*; Ma, D*; Jiang, H*; Lin, L; Yao, L; Samurkas, A; Li, Y; Wang, Y; Cao, P; Wu, S; Zhang, Y; Murayama, T; Moussian, B; Van Petegem, F; Yuchi Z
Structural basis for diamide modulation of ryanodine receptor
Nat Chem Biol. 16(11): 1246-1254.
2019
2018
Haji-Ghassemi, O; Müller-Loennies, S; Brooks, CL; MacKenzie, CR; Caveney, N; Van Petegem, F; Brade, L; Kosma, P; Brade, H; Evans, SV
Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude
Biochemistry. 58(6): 714-726.
Roston, T*; Haji-Ghassemi O*; LaPage, MJ; Batra, AS; Bar-Cohen, Y; Anderson, C; Lau, YR; Maginot, K; Gebauer, RA; Etheridge, SP; Potts, JE; Van Petegem, F; Sanatani S
Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry
Plos One. 13(11): e0205925.
Blackler, RJ; López-Guzmán, A; Hager, FF; Janesch, B; Martinz, G; Gagnon, SML; Haji-Ghassemi, O; Kosma, P; Messner, P; Schäffer, C; Evans, SV
Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei
Nat Commun. 9(1): 3120.
Gagnon, SML; Legg, MSG; Polakowski, R; Letts, JA; Persson, M; Lin, S; Blake Zheng, R; Rempel, B; Schuman, B; Haji-Ghassemi, O; Borisova, SN; Palcic, MM; Evans, SV
Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases
Glycobiology. 28(8): 624-636.
2016
Haji-Ghassemi, O; Gilbert, M; Spence, J; Schur, MJ; Parker, MJ; Jenkins, ML; Burke, JE; van Faassen, H; Young, MN; Evans, SV
Molecular basis for recognition of the cancer glycobiomarker, GalNAc(β1-4)GlcNAc (LacdiNAc) by Wisteria floribunda agglutinin
J Biol Chem. 291(46): 24085-24095.
Haji-Ghassemi, O; Müller-Loennies, S; Rodriguez, T; Brade, L; Grimmecke, HD; Brade, H; Evans, SV
The Combining Sites of Anti-lipid A Antibodies Reveal a Widely Utilized Motif Specific for Negatively Charged Group
J Biol Chem. 291: 10104-10118.
2015
Haji-Ghassemi, O; Müller-Loennies, S; Rodriguez, T; Brade, L; Kosma, P; Brade, H; Evans, SV
Structural basis for antibody recognition of lipid A: insights to polyspecificity toward single stranded DNA
J Biol Chem. 290: 19629-196240.
Haji-Ghassemi, O; Blackler, RJ; Young, MN; Evans, SV
Antibody recognition of carbohydrate epitopes
Glycobiology. 25(9): 920-952. [Review]
2014
Haji-Ghassemi, O; Müller-Loennies, S; Saldova, R; Muniyappa, M; Brade, L; Rudd, PM; Harvey, DJ; Kosma, P; Brade, H; Evans, SV
Groove-type recognition of chlamydiaceae-specific lipopolysaccharide antigen by a family of antibodies possessing an unusual variable heavy chain N-linked glycan
J Biol Chem. 289(24): 16644-16661.
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